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Risk factors in coronary atherosclerosis athero-inflammation: the meeting point

Raul Altman email

Centro de Trombosis de Buenos Aires and Catedra de Magister en Trombosis, Facultad de Medicina, Universidad Nacional de Tucuman, Argentina

author email corresponding author email

Thrombosis Journal 2003, 1:4doi:10.1186/1477-9560-1-4

Published: 17 July 2003

First paragraph (this article has no abstract)

Following Russel Ross [1], there is now general agreement that vessel wall inflammation constitutes a major factor in the development of atherosclerosis, atheroma instability and plaque disruption followed by local thrombosis, that underlies the clinical presentation of acute coronary syndromes [2-4]. Endothelial-cell injury is the main stimulus for development of the atherosclerotic plaque: an inflammatory-fibroproliferative response results from various forms of insult to the endothelium.


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