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Comparison of histomorphometric measurements and ex vivo MRI visible coronary artery thrombus features of coronary artery serial segments. % aorta wall thickness (mm), atheroma size (mm2) and total plaque volume(mm3) were measured by superimposed delineation of area on both histology and MRI images. |
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| Rabbit slicea Rabbit segmentb % difference |
Total artery radius and area |
% Aorta wall thickness (mm) |
Atheroma area (mm2) |
% Stenosis |
Plaque Volume (mm3) |
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| Outer Radius (mm)/ Area (mm2) |
Lumen Radius (mm)/ Area (mm2 |
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|
|
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| 115_1 |
1.70 |
9.08 |
1.47 |
6.79 |
25.22 |
-- |
-- |
1.95 |
| 115_seg0.5 |
1.69 |
8.97 |
1.46 |
6.69 |
25.93 |
0.68 |
10.0 |
1.92 |
| % difference |
1.0 |
1.2. |
0.68 |
10.0 |
2.73 |
1.53 |
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| 120_4 |
1.69 |
8.97 |
1.42 |
6.33 |
29.43 |
0.82 |
12.9 |
2.10 |
| 120_seg1.5 |
1.68 |
8.87 |
1.41 |
6.24 |
29.65 |
0.78 |
12.5 |
1.99 |
| % difference |
1.00 |
1.11 |
0.70 |
1.42 |
0.74 |
4.87 |
3.10 |
5.24 |
| 123_3 |
1.68 |
8.87 |
1.42 |
6.33 |
28.63 |
0.92 |
14.50 |
2.50 |
| 123_seg1.5 |
1.67 |
8.76 |
1.39 |
6.07 |
30.70 |
0.86 |
14.16 |
2.60 |
| % difference |
0.59 |
1.24 |
2.11 |
4.10 |
7.23 |
6.52 |
2.34 |
3.84 |
| 123_6 |
1.71 |
9.18 |
1.33 |
5.55 |
39.55 |
1.14 |
20.54 |
2.80 |
| 123_seg1.0 |
1.70 |
9.08 |
1.30 |
5.30 |
41.62 |
1.12 |
21.13 |
2.35 |
| % difference |
0.58 |
1.09 |
2.25 |
4.50 |
4.97 |
1.75 |
2.79 |
16.0 |
| 133_2 |
1.68 |
8.87 |
1.35 |
5.73 |
35.40 |
0.84 |
14.65 |
2.20 |
| 133_seg2.0 |
1.66 |
8.65 |
1.30 |
5.30 |
38.73 |
0.82 |
15.47 |
2.15 |
| % difference |
1.19 |
2.48 |
3.70 |
7.50 |
9.32 |
2.38 |
5.30 |
2.27 |
| 133_4 |
1.67 |
8.76 |
1.42 |
6.33 |
27.74 |
0.86 |
13.58 |
1.80 |
| 133_seg2.5 |
1.66 |
8.65 |
1.34 |
5.64 |
34.80 |
0.74 |
13.12 |
1.65 |
| % difference |
0.59 |
1.25 |
5.63 |
10.9 |
20.2 |
13.9 |
3.38 |
8.33 |
| 145_6 |
1.78 |
9.18 |
1.50 |
7.07 |
22.98 |
-- |
-- |
|
| 145_seg2 |
1.67 |
8.76 |
1.45 |
7.00 |
20.10 |
0. 44 |
6.2 |
0.40 |
| % difference |
6.17 |
4.57 |
3.33 |
1.0 |
12.53 |
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| 145_8 |
1.80 |
10.18 |
1.30 |
5.30 |
47.93 |
1.18 |
22.26 |
2.60 |
| 145_seg4 |
1.77 |
9.84 |
1.28 |
5.14 |
47.76 |
1.06 |
20.62 |
2.35 |
| % difference |
1.66 |
3.33 |
1.54 |
3.02 |
0.36 |
10.1 |
7.36 |
9.61 |
| 195_4 |
1.72 |
9.29 |
1.40 |
6.15 |
33.70 |
0.76 |
12.35 |
2.55 |
| 195_seg2.5 |
1.70 |
9.08 |
1.37 |
5.89 |
35.10 |
0.77 |
13.07 |
2.80 |
| % difference |
1.11 |
2.26 |
2.14 |
4.22 |
3.98 |
1.31 |
5.50 |
8.92 |
| 195_10 |
1.77 |
9.84 |
1.39 |
6.07 |
38.31 |
0.84 |
13.83 |
2.75 |
| 195_seg |
1.67 |
8.76 |
1.37 |
5.90 |
32.64 |
0.80 |
13.56 |
2.68 |
| % difference |
5.65 |
10.9 |
1.43 |
2.80 |
14.80 |
4.76 |
1.95 |
2.54 |
| 195_12 |
1.70 |
9.08 |
1.36 |
5.81 |
36.0 |
0.46 |
11.1 |
1.80 |
| 195_seg |
1.68 |
8.87 |
1.32 |
5.47 |
38.3 |
0.42 |
11.3 |
2.00 |
| % difference |
1.10 |
2.31 |
2.94 |
5.85 |
6.00 |
8.69 |
1.76 |
11.1 |
| 195_14 |
1.72 |
9.29 |
1.32 |
5.47 |
41.11 |
0.58 |
10.60 |
1.80 |
| 195_seg |
1.71 |
9.18 |
1.33 |
5.55 |
39.54 |
0.60 |
10.81 |
1.55 |
| % difference |
0.58 |
1.18 |
0.75 |
1.44 |
3.82 |
3.33 |
1.94 |
3.12 |
| 198_3 |
1.71 |
9.18 |
1.36 |
5.47 |
40.4 |
1.14 |
28.84 |
2.20 |
| 198_seg1.5 |
1.67 |
8.76 |
1.30 |
5.30 |
39.5 |
1.10 |
20.75 |
2.10 |
| % difference |
2.33 |
4.57 |
4.41 |
3.10 |
2.22 |
3.50 |
28.0 |
4.54 |
| 198_5 |
1.68 |
8.87 |
1.39 |
6.06 |
31.68 |
1.15 |
18.97 |
1.20 |
| 198_seg2.0 |
1.60 |
8.04 |
1.34 |
5.64 |
29.85 |
1.12 |
19.86 |
1.55 |
| % difference |
16.6 |
9.35 |
3.59 |
6.93 |
5.77 |
2.60 |
4.48 |
4.16 |
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aRabbit number and magnetic resonance microimage slice number(1 mm thick). bRabbit number and coronary tissue segment containing corresponding MRM slice(5 mm thick). | ||||||||
Sharma and Singh Thrombosis Journal 2004 2:5 doi:10.1186/1477-9560-2-5 |
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