|
Comparison of sampling techniques for different coagulation parameters: Vena cava puncture (VCP) vs heart puncture (HP) as measured by Soluble Fibrin in plasma of untreated negative control mice |
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| Number of mice negative |
Number of mice with borderline result |
Number of mice positive |
Number of mice analyzed |
Number of positive results in negative control mice |
|
|
|
|||||
| sampling technique: |
n |
n |
n |
n |
% |
|
|
|||||
| VCP 1:5 |
17 |
1 |
0 |
18 |
0 % |
| VCP 1:10 |
10 |
2 |
5 |
17 |
29% |
| HP 1:5 |
0 |
0 |
5 |
5 |
100% |
| HP 1:10 |
3 |
0 |
10 |
13 |
77% |
| Ref.values: |
neg‡ |
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|
‡ negative, if no further manipulations are performed. If reagents are administered i.v., there can be up to 30% positive samples, independent of the reagent applied (see Fig. 2). | |||||
Unruh et al. Thrombosis Journal 2005 3:21 doi:10.1186/1477-9560-3-21 |
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