Table 1

Causes of genetic thrombophilia

Established genetic factors
Rare genetic factors
Indeterminate factors

Factor V Leiden
Dysfibrinogenemias
Elevated Factor VIII
Prothrombin G20210A
Hyperhomocysteinemia
Elevated Factor IX
Protein C deficiency

Elevated Factor XI
Protein S deficiency

Plasminogen deficiency
Antithrombin deficiency

Tissue plasminogen activator


Elevated lipoprotein a


Factor VII


Factor XII


Platelet glycoprotein


Plasminogen activator inhibitor


Heparin cofactor II


Thrombomodulin


Histidine-rich glycoprotein

Khan and Dickerman Thrombosis Journal 2006 4:15   doi:10.1186/1477-9560-4-15