|
Prevalence of genetic defects among Caucasians [15] |
||||
| Incident VTE (%) |
Recurrent VTE (%) |
Normal population |
Relative thrombotic risk |
|
|
|
||||
| Activated Protein C resistance (Factor V Leiden) |
20 |
40–50 |
3–7 |
3–7 heterozygotes 50–100 homozygotes |
| Prothrombin G20210A mutation |
3–8 |
15–20 |
1–3 |
2–8 heterozygotes |
| Antithrombin deficiency |
1–2 |
2–5 |
0.02–0.04 |
5 |
| Protein C deficiency |
2–5 |
5–10 |
0.2–0.5 |
6–10 |
| Protein S deficiency |
1–3 |
5–10 |
0.1–1 |
2 |
Khan and Dickerman Thrombosis Journal 2006 4:15 doi:10.1186/1477-9560-4-15 |
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