Table 3

Mutational state frequence for FV R506Q, PT G20210A, MTHFR C677T, PAI-1 4G/5G, ACE I/D genes in patients and healhty subjects (HS).

Gene coagulation mutations
Homozygous Wilde-type
Heterozygous
Homozygous Mutated


Patients (17)
HS (51)
Patients (17)
HS (51)
Patients (17)
HS (51)
FV R506Q
94%
98%
6%
2%
-
-
PT G20210A
94%
98%
6%
2%
-
-
MTHFR C677T
41%
57%
41%
31%
18%
12%
PAI-1 4G/5G
47%
30%
35%
51%
18%
19%
ACE I/D
30%
46%
47%
43%
23%
11%

FV R506Q: factor V Leiden gene polimorphism

PT G20210A: prothrombin G20210A gene polymorphism

MTHFR C677T: Methylenetetrahydrofolate reductase C677T gene polymorphism

PAI-1 4G/5G: plasminogen activator inihibitor 1 4G\5G gene polymorphism

ACE I\D: angiotensin converting enzyme insertion\deletion gene polymorphism

De Lucia et al. Thrombosis Journal 2006 4:21   doi:10.1186/1477-9560-4-21