|
Proinflammatory SNPs stratified by smoking status demonstrating the number of cases and controls, and Odds Ratio, 95%CI and p-values in an age-, race-adjusted additive model. |
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| Gene |
rs number |
Smokers |
Non-Smokers |
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|
|
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| Cases/Controls |
OR* |
95% CI |
p-value |
Cases/Controls |
OR* |
95% CI |
p-value |
||
|
|
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| CD14 |
rs2569190 |
77/31 |
2.05 |
1.09–3.87 |
0.027 |
82/121 |
0.93 |
0.62–1.39 |
0.72 |
| IL1A |
rs17561 |
106/48 |
1.68 |
0.84–3.32 |
0.14 |
111/156 |
1.05 |
0.69–1.60 |
0.83 |
| IL1R1 |
rs3917318 |
102/45 |
1.138 |
0.67–1.94 |
0.64 |
108/155 |
1.07 |
0.74–1.54 |
0.72 |
| IL1B |
rs3917365 |
99/44 |
1.63 |
0.78–3.42 |
0.19 |
105/146 |
1.03 |
0.62–1.73 |
0.90 |
| IL6 |
rs1800797 |
104/43 |
1.28 |
0.66–2.46 |
0.46 |
110/155 |
1.05 |
0.67–1.64 |
0.83 |
| rs2069830 |
103/45 |
1.63 |
0.48–5.58 |
0.43 |
109/155 |
0.30 |
0.11–0.82 |
0.019 |
|
| rs2069832 |
101/45 |
0.69 |
0.35–1.35 |
0.28 |
109/152 |
0.80 |
0.51–1.26 |
0.34 |
|
| MMP3 |
rs679620 |
103/46 |
0.98 |
0.58–1.65 |
0.93 |
110/157 |
1.01 |
0.71–1.43 |
0.97 |
|
* Adjusted for age and race (African-American, Caucasian, and other). | |||||||||
Cole et al. Thrombosis Journal 2008 6:11 doi:10.1186/1477-9560-6-11 |
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