|
Bleeding events according to CYP2C9 and VKORC1 genotype. |
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| CYP2C9 genotype |
VKORC1 genotype |
N (%) |
Mean INR (95% C.I.) |
Major/minor bleeding events N (%) |
Occult bleeding events N (%) |
Total bleeding events N (%) |
|
|
||||||
| *1/*1 |
C/C |
33 (31.4) |
2.65 (2.45–2.84) |
2 (6.1) |
4 (12.1) |
6 (18.2) |
| C/T |
28 (26.7) |
2.79 (2.60–2.99) |
3 (10.7) |
5 (17.9) |
8 (28.6) |
|
| T/T |
12 (11.4) |
2.71 (2.37–3.05) |
2 (16.7) |
- |
2 (16.7) |
|
| *1/*2,*3 |
C/C |
8 (7.6) |
2.58 (2.19–2.96) |
- |
1 (12.5) |
1 (12.5) |
| C/T |
16 (15.2) |
2.83 (2.55–3.10) |
2 (12.5) |
4 (25.0) |
6 (37.5) |
|
| T/T |
3 (2.9) |
2.87 (2.49–3.25) |
||||
| *2/*2,*3 |
C/C |
2 (1.9) |
2.30 (1.03–3.57) |
|||
| C/T |
2 (1.9) |
2.15 (0.24–4.06) |
||||
| T/T |
1 (1.0) |
3.50 |
||||
|
|
||||||
| Total |
105 (100) |
9 |
14 |
23 |
||
Haug et al. Thrombosis Journal 2008 6:7 doi:10.1186/1477-9560-6-7 |
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