Case report

Aminaphtone in the control of Schamberg's disease

José Maria Pereira de Godoy¹ and Fernando Batigália²

¹  Angiology and Vascular Surgery Service, São José do Rio Preto Medicine School, SP (FAMERP), Brazil

²  São José do Rio Preto Medicine School, SP (FAMERP), Brazil

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Thrombosis Journal 2009, 7:8doi:10.1186/1477-9560-7-8

Published:	11 June 2009

Abstract

The aim of this case report is to describe control of Schamberg's disease using aminaphtone. We report on the case of a 28-year-old patient who presented with multiple purpuric lesions of the lower extremities which had appeared spontaneously. A biopsy of the skin was performed that showed a perivascular T-cell lymphocytic infiltrate centered on the small superficial blood vessels of the skin and so a diagnosis of Schamberg's disease was reached. The patient was prescribed corticoids and the lesions disappeared however on suspension of the medication the lesions re-emerged within three to seven days. This treatment was unsuccessfully continued for more than one year. Thus another therapeutic option was attempted: 75 mg of aminaphtone was prescribed twice daily for one month and the purpuric lesions disappeared within about one week. One year after suspending the medication no relapse of the purpura was observed.