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Vascular restenosis. Basic science and clinical implications.

Heckenkamp J, Gawenda M, Brunkwall J.

Department of Surgery, Division of Vascular Surgery, University of Cologne, Cologne, Germany. j_heckenkamp@hotmail.com

Cardiovascular interventions to correct arterial occlusive disease have excellent short-term results, but long-term patency is still seriously compromised by the development of restenosis. This review will provide a portrait of the mechanisms following vascular injury, define the clinical scope of the problem and outline developments of different therapeutical strategies to prevent restenosis.

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PMID: 12055567 [PubMed - indexed for MEDLINE]