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Postpartum deep vein thrombosis and pulmonary embolism in twin pregnancy: undertaking of clinical symptoms leading to massive complications

Leslie Fiengo13*, Federico Bucci2, Gregorio Patrizi1, Domenico Giannotti1 and Adriano Redler1

Author Affiliations

1 Department of Vascular Surgery, La Sapienza University of Rome, Rome, Italy

2 Vascular Surgery Department, Centre Hospitalier Sud Gironde, Langon, France

3 Dipartimento Scienze Chirurgiche-Università La Sapienza, Viale Regina Elena, 324-00161, Rome, Italy

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Thrombosis Journal 2013, 11:4  doi:10.1186/1477-9560-11-4

Published: 22 February 2013



Deep Vein Thrombosis (DVT) is an important cause of morbidity and is the first cause of maternal death after delivery in Western Nations. The risk of venous thromboembolism is present throughout the pregnancy and is maximal during postpartum, especially after twin delivery. Many of the signs and symptoms of DVT overlap those of a normal pregnancy causing difficulty for diagnosis.

Case report

We report the case of a 33 year-old woman transferred to our Department one week after caesarean section for twin delivery. She presented with severe abdominal pain, fever, abdominal distension and shortness of breath. She had no personal or family history of thromboembolism. Computerized Tomography Scan revealed right ovarian vein thrombosis, left renal vein thrombosis extending up to the Inferior Vena Cava and pulmonary embolism with bilateral pleural effusion. Caval filter was positioned and anticoagulation therapy associated with antibiotics was instituted. Pancreatitis showed up two days after and was promptly treated. Three months after discharge the caval filter was removed and oral anticoagulation was stopped. During a 12-months follow-up, she remained stable and symptom free.


Ovarian vein thrombosis is rare but recognition of signs and symptoms is fundamental to start adequate therapy and avoid potential serious sequelae. The risk for maternal postpartum ovarian vein thrombosis is increased by caesarean section delivery of twins. Such patients should be closely monitored. We illustrated how an underestimated condition can lead to massive complications.

Twin delivery; Postpartum ovarian vein thrombosis; Pulmonary emboli